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FORMATE-TETRAHYDROFOLATE LIGASE
Descriptors Found:
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DeCS
Descriptor
English
:
Formate-Tetrahydrofolate Ligase
Descriptor
Spanish
:
Formiato-Tetrahidrofolato Ligasa
Descriptor
Portuguese
:
Formiato-Tetraidrofolato Ligase
Synonyms
English
:
Tetrahydrofolate Formylase
Tree Number:
D08.811.464.259.550
Definition
English
:
A carbon-nitrogen ligase that catalyzes the formation of 10-formyltetrahydrofolate from formate and tetrahydrofolate in the presence of ATP. In higher eukaryotes the enzyme also contains METHYLENETETRAHYDROFOLATE DEHYDROGENASE (NADP+) and
METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE
activity.
See Related
English
:
Methenyltetrahydrofolate Cyclohydrolase
Methylenetetrahydrofolate Dehydrogenase (NADP)
History Note
English
:
98(75)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
5709
Unique Identifier:
D005574
Occurrence in VHL
:
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CID-10
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